What is Simvastatin? Simvastatin (Zocor) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." It reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Simvastatin is used to lower cholesterol and triglycerides (types of fat) in the blood. It is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors. Simvastatin is used in adults and children who are at least 10 years old.
About Simvastatin: Before taking simvastatin, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, if you are of Chinese descent, or if you drink more than 2 alcoholic beverages daily. Do not use if you are pregnant.
Simvastatin can cause a condition resulting in the breakdown of skeletal muscle tissue, leading to kidney failure. Never take simvastatin in larger amounts, or for longer than recommended by your doctor. Taking too much of simvastatin may cause serious or life-threatening side effects.
What to Avoid While Taking Simvastatin: Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Do not drink more than 1 quart of grapefruit juice daily. Avoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.
Side effects: Allergic reactions include hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking simvastatin call your doctor immediately if you have any of these serious side effects: unexplained muscle pain, tenderness, or weakness; fever, unusual tiredness, and dark colored urine; pain or burning when you urinate; swelling, weight gain, urinating less than usual or not at all; nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). headache; joint pain, mild muscle pain; constipation, stomach pain or indigestion, mild nausea; mild skin rash; sleep problems (insomnia); or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. http://www.drugs.com/simvastatin.html
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