Clostridium difficile (klos-TRID-e-um dif-uh-SEEL), C. difficile or C. diff, is a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.
Illness
from C. difficile most commonly affects older adults in hospitals or in
long-term care facilities and typically occurs after use of antibiotic medications.
C. difficile infections have become more frequent severe and difficult to
treat. http://www.mayoclinic.com/health/c-difficle/DS00736
For mild
to moderate infection, doctors usually prescribe metronidazole (Flagyl) is not
FDA approved for C. difficile infection but has been shown to be effective.
Side effects include nausea and a bitter taste in your mouth.
Antibiotics:
Ironically the standard treatment for C.
difficile is another antibiotic. These antibiotics keep C. difficile from
growing, which treats diarrhea and other complications.
For more
severe and recurrent cases, vancomycin (Vancocin) may be prescribed. Another
oral antibiotic, fidaxomicin (Dificid). In a study the recurrence rate of C.
difficile in people who took fidaxomicin was lower than among those who took vancomycin.
Fidaxomicin costs considerably more than metronidazole and vancomycin. Common
side effects of vancomycin and fidaxomicin include abdominal pain and nausea.
Surgery:
For people with severe pain, organ failure or inflammation of the lining of the
abdominal wall, surgery to remove the diseased portion of the colon may be the
only option.
Recurrent Infection
Up to 20 percent of people with C. difficile get sick again, either because the initial infection never went away or because they're re-infected with a different strain of the bacteria. Treatment for recurrent disease may include:
Up to 20 percent of people with C. difficile get sick again, either because the initial infection never went away or because they're re-infected with a different strain of the bacteria. Treatment for recurrent disease may include:
Antibiotics:
Antibiotic therapy for recurrence may involve one or more courses of a
medication (typically vancomycin).
Fecal microbiota transplant (FMT): Also known as a stool
transplant, though not yet approved by the FDA, clinical studies of FMT are
currently underway. Research has shown FMT has a success rate higher than 90
percent for treating C. difficile infections. One small, randomized, controlled
trial stopped early because the results were so positive, with a 94 percent
success rate overall.
Probiotics: Probiotics
are organisms, such as bacteria and yeast, which help restore a healthy balance
to the intestinal tract. A yeast called Saccharomyces boulardii, in conjunction
with antibiotics, might help prevent further recurrent C. difficile infections. http://www.mayoclinic.com/health/c-difficile/DS00736/DSECTION=treatments-and-drugs
Herbal Treatment
Check
with your doctor before taking any herb to treat a Clostridium difficile
infection.
Garlic has been used for more than 5,000 years as
an herbal healer, according to Michael Castleman, author of "The New
Healing Herbs." The antibiotic properties of garlic's primary chemical
compound, called allicin, may help destroy Clostridium difficile infection. It
may promote excessive wound bleeding by reducing your body's ability to produce
blood platelets.
Catnip is not widely used as an herbal
remedy in the United States today. Early Americans used this herb to treat
depression, according to Castleman. Nepetalactone isomers, which are chemicals
found in catnip, may offer antibiotic benefits. These chemicals may help
control the growth and spread of Clostridium difficile, helping to relieve diarrhea
and abdominal pain associated with infection.
CayenneThis hot pepper also has a long
history of use in herbal medicine. Capsaicin, the primary chemical compound in
cayenne, may also help destroy Clostridium difficile bacteria, reducing
infection. Handling fresh cayenne peppers may cause skin burns, and may
irritate the mucous linings of your nose and eyes. http://www.livestrong.com/article/489748-herbal-remedies-for-c-diff/#ixzz2byGGeq2b
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